We study principles of tissue morphogenesis using zebrafish.
Our science is collaborative and crosses disciplines. Our culture is integrative and inclusive.

Video highlighting the multi-scale dynamics of inner ear morphogenesis in a 2 day old zebrafish embryo

Morphogenesis is the process by which simple tissues form complex shapes. Successful embryonic development critically depends on forming proper shapes - failure to do so can be fatal or cause developmental defects. What are the principles of healthy tissue morphogenesis and what are the mechanisms underlying disease etiology? We deploy integrative systems approaches, including quantitative imaging, genetics, multi-scale perturbations, theoretical modeling and single cell RNA sequencing, to study principles of morphogenesis using the embryonic zebrafish inner ear.